Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | BHMT | Q93088 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17822696 | 0.91 | GPR84 (0.58) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL18771046 | 0.91 | GPR84 (0.58) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL7509590 | 0.90 | CAMK2A (0.62) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL756105 | 0.89 | TSHR (0.71) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL31241576 | 0.87 | TSHR (0.68) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL3366538 | 0.84 | — | — | |
| SCHEMBL6866613 | 0.84 | LMNA (0.78) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL197330 | 0.82 | — | — | |
| SCHEMBL2280524 | 0.81 | LMNA (0.65) | TSHRLMNATDP1KMT2AHSD17B10 | |
| SCHEMBL2596733 | 0.81 | GPR84 (0.65) | TSHRLMNATDP1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686613-B1 | OZONIDE REDUCING AGENT | OTSUKA KAGAKU KK (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-5770729-A | SULFIDE COMPOUND WITH POLAR SUBSTITUENTS, FORMATION OF SULFOXIDE, MILD CONDITIONS, SAFE, NONPOLLUTING | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0686613-A1 | OZONIDE REDUCING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |
| EP-0404949-A1 | SUBSTITUTED ACETAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND ANTIULCER DRUG CONTAINING SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |