Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.65 |
| ▸ | HRH2 | P25021 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clobenpropit SCHEMBL8312286 | 0.76 | HRH4 (0.40) | HRH4HRH3HRH2TP53CYP1A2 | |
| Clobenpropit SCHEMBL49050 | 0.75 | HRH4 (1.00) | HRH4HRH3TP53CYP1A2CYP3A4 | |
| Clobenpropit SCHEMBL15130115 | 0.75 | HRH4 (0.42) | HRH4HRH3HRH2TP53CYP1A2 | |
| SCHEMBL8624867 | 0.74 | HRH3 (0.56) | HRH4HRH3HRH2 | |
| Clobenprobit SCHEMBL29613706 | 0.73 | HRH4 (0.38) | HRH4HRH3HRH2CYP2C9CYP2C19 | |
| SCHEMBL2741604 | 0.71 | HRH4 (0.68) | HRH4HRH3 | |
| SCHEMBL194703 | 0.69 | HRH3 (0.71) | HRH4HRH3 | |
| SCHEMBL12648563 | 0.68 | KMT2A (0.35) | HRH4HRH3CYP2C9CYP2C19 | |
| SCHEMBL1334242 | 0.67 | HRH3 (0.58) | HRH3 | |
| SCHEMBL8620792 | 0.66 | HRH4 (0.58) | HRH4HRH3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190175557-A1 | COMPOUNDS USEFUL FOR DECREASING INTERFERON LEVEL | UNIVERSITÉ PARIS CITÉ (FR) | 2019-06-13 | — | — | US | disclosed |
| WO-2017216368-A1 | COMPOUNDS USEFUL FOR DECREASING INTERFERON LEVEL | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190175557-A1 | COMPOUNDS USEFUL FOR DECREASING INTERFERON LEVEL | IFNAR1, CXCR4, CXCR3 | HRH4 515/4885HRH3 667/4885HRH2 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.