Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.58 |
| ▸ | HRH2 | P25021 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624867 | 0.89 | HRH3 (0.56) | HRH4HRH2HRH3 | |
| SCHEMBL14914554 | 0.75 | ST14 (0.47) | — | |
| SCHEMBL11398008 | 0.73 | TAAR1 (0.50) | HRH4HRH3 | |
| SCHEMBL8964986 | 0.72 | HRH3 (0.79) | HRH4HRH2HRH3 | |
| SCHEMBL8963957 | 0.70 | HRH3 (0.80) | HRH4HRH2HRH3 | |
| SCHEMBL2536900 | 0.70 | HRH3 (0.93) | HRH4HRH2HRH3 | |
| SCHEMBL11036080 | 0.69 | HRH4 (0.86) | HRH4HRH2HRH3 | |
| SCHEMBL8963886 | 0.68 | HRH3 (0.75) | HRH4HRH2HRH3 | |
| SCHEMBL7765126 | 0.68 | MEN1 (0.74) | HRH4HRH2 | |
| SCHEMBL7567011 | 0.67 | QPCT (0.71) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837718-A | ANTIHISTAMINES | SEED CAPITAL INVESTMENT (SCI) B.V. (NL) | 1998-11-17 | — | — | US | disclosed |