Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 10/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201458 | 0.74 | LMNA (0.33) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL21065691 | 0.74 | NPC1 (0.34) | LMNAMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL24865833 | 0.74 | NPC1 (0.37) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL3453648 | 0.74 | LMNA (0.36) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL27662180 | 0.74 | KMT2A (0.42) | LMNASMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL25774868 | 0.74 | HSD17B3 (0.51) | HSD17B3SMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL19198881 | 0.72 | HSD17B3 (0.42) | HSD17B3LMNATSHRMAPK1SCN4A | |
| SCHEMBL22297598 | 0.72 | LMNA (0.41) | HSD17B3LMNATSHRMAPK1SCN4A | |
| SCHEMBL20149218 | 0.72 | HSD17B3 (0.39) | HSD17B3LMNATSHRMAPK1SCN4A | |
| SCHEMBL31021296 | 0.71 | DRD3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023065137-A1 | SITE-SPECIFIC GLYCOPROTEIN CONJUGATES AND METHODS FOR MAKING THE SAME | GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) | 2023-04-27 | — | — | WO | disclosed |
| US-10335495-B2 | Biomolecule conjugates | CELGENE CORPORATION (US) | 2019-07-02 | — | — | US | disclosed |
| WO-2017218796-A1 | METABOLIC LABELING AND MOLECULAR ENHANCEMENT OF BIOLOGICAL MATERIALS USING BIOORTHOGONAL REACTIONS | OTT HARALD C (US) | 2017-12-21 | — | — | WO | disclosed |
| US-20170360952-A1 | BIOMOLECULE CONJUGATES | CELGENE CORPORATION | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10335495-B2 | Biomolecule conjugates | DNPEP, NAPA, NCL | HSD17B3 4314/4885LMNA 2251/4885TSHR 2150/4885 |
| US-20170360952-A1 | BIOMOLECULE CONJUGATES | DNPEP, NAPA, NCL | HSD17B3 4314/4885LMNA 2251/4885TSHR 2150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.