Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666817 | 0.85 | CYP1A2 (0.54) | CYP1A2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31689764 | 0.84 | KMT2A (0.36) | CYP1A2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29098754 | 0.83 | CYP1A2 (0.52) | CYP1A2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10930717 | 0.82 | MAPT (0.33) | CYP1A2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27705418 | 0.82 | CYP1A2 (0.50) | CYP1A2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2427468 | 0.81 | CYP1A2 (0.48) | CYP1A2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1204591 | 0.77 | CYP1A2 (0.56) | CYP1A2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4659349 | 0.76 | CYP1A2 (0.59) | CYP1A2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10929141 | 0.76 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL1456160 | 0.74 | ALDH1A1 (0.50) | CYP1A2ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140206531-A1 | Activation of Porous MOF Materials | NORTHWESTERN UNIVERSITY (US) | 2014-07-24 | — | — | US | disclosed |
| US-20130237412-A1 | Activation of Porous MOF Materials | NORTHWESTERN UNIVERSITY (US) | 2013-09-12 | — | — | US | disclosed |
| US-8426624-B2 | Activation of porous MOF materials | NORTHWESTERN UNIVERSITY (US) | 2013-04-23 | — | — | US | disclosed |
| US-20110144367-A1 | Activation of porous MOF materials | NORTHWESTERN UNIVERSITY | 2011-06-16 | — | — | US | disclosed |