SCHEMBL1204591

SCHEMBL1204591

O=C(O)c1ccc(C(=O)O)c2c(C(=O)O)c(Cl)cc(C(=O)O)c12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
TSHR P16473 5/20 0.48
CASP1 P29466 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 6/20 0.44
TP53 P04637 1/20 0.44
KDM4E B2RXH2 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPT P10636 2/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
DPP4 P27487 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40
MYC P01106 1/20 0.39
NR4A1 P22736 1/20 0.39
AKR1C2 P52895 2/20 0.38
AKR1C1 Q04828 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24455 0.92 ALDH1A1 (0.45) CYP1A2TSHRCASP1SMN1; SMN2ALDH1A1
SCHEMBL29764017 0.92 ALDH1A1 (0.45) CYP1A2TSHRCASP1SMN1; SMN2ALDH1A1
SCHEMBL30254 0.90 CYP1A2 (0.44) CYP1A2TSHRCASP1SMN1; SMN2ALDH1A1
SCHEMBL29764032 0.90 CYP1A2 (0.44) CYP1A2TSHRCASP1SMN1; SMN2ALDH1A1
SCHEMBL31401887 0.86 ALDH1A1 (0.41) CYP1A2TSHRCASP1SMN1; SMN2ALDH1A1
SCHEMBL5947642 0.81 CYP1A2 (0.64) CYP1A2TSHRCASP1SMN1; SMN2ALDH1A1
SCHEMBL31115305 0.81 CYP1A2 (0.64) CYP1A2TSHRCASP1SMN1; SMN2ALDH1A1
SCHEMBL6738393 0.81 ALDH1A1 (0.37) CYP1A2TSHRCASP1SMN1; SMN2ALDH1A1
SCHEMBL6735101 0.79 ALDH1A1 (0.36) CYP1A2TSHRCASP1SMN1; SMN2ALDH1A1
SCHEMBL2904787 0.79 DPP4 (0.46) CYP1A2TSHRCASP1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106700965-A Anisotropic conductive adhesive and method for producing same, circuit connecting structure body and application 日立化成株式会社 2017-05-24 CN claimed
CN-110050371-A Gas diffusion layer for fuel cell including porous carbon film layer 凯得内株式会社 2019-07-23 CN disclosed
CN-108300350-A Flexible flat cable reinforcing plate film 杜邦-东丽株式会社 2018-07-20 CN disclosed
CN-107880802-A polyimide film with adhesive 杜邦-东丽株式会社 2018-04-06 CN disclosed
CN-106479176-A Polyimide film and its manufacture method 杜邦-东丽株式会社 2017-03-08 CN disclosed
US-8202674-B2 Polymers of napthalene tetracarboxylic diimide dimers XEROX CORPORATION (US) 2012-06-19 US disclosed
CN-101523250-B Optical film, image display, diethynyl fluorene and polymer of the diethynyl fluorene NITTO DENKO CORP 2011-08-24 CN disclosed
CN-101122648-B Polarizing film, laminated film, and liquid crystal display NITTO DENKO CORP 2011-05-04 CN disclosed
CN-101176031-B Liquid crystal panel and liquid crystal display employing same NITTO DENKO CORP 2011-03-30 CN disclosed
US-20110028724-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2011-02-03 US disclosed
CN-1636153-A Laminated retardation plate, laminated polarizing plate using the same, and image display NITTO DENKO CORP (JP) 2005-07-06 CN disclosed
CN-1633613-A Inclined optical compensation film method for producing the same and liquid crystal display including the same NITTO DENKO CORP (JP) 2005-06-29 CN disclosed
CN-1623107-A Optical film, laminated polarizing plate, liquid crystal display using the same, and self-light-emitting display using the same NITTO DENKO CORP (JP) 2005-06-01 CN disclosed
US-20050004365-A1 Naphthalene tetracarboxylic diimide dimers XEROX CORPORATION 2005-01-06 US disclosed
US-6794102-B2 ELECTROPHOTOGRAPHIC ELEMENTS XEROX CORPORATION 2004-09-21 US disclosed
CN-1508606-A Double-refraction optical film, elliptic polarizing piece using same, and liquid crystal display using said polarizing piece 日东电工株式会社 2004-06-30 CN disclosed
CN-1508607-A Double-refraction optical film, elliptic polarizing piece using same and liquid crystal display using said polarizing piece �ն��繤��ʽ���� 2004-06-30 CN disclosed
US-20040013959-A1 Naphthalene tetracarboxylic diimide dimers XEROX CORPORATION 2004-01-22 US disclosed
EP-0362649-A2 Radiation-sensitive compositions and their use BASF Aktiengesellschaft (DE) 1990-04-11 EP disclosed
EP-0362644-A1 Radiation-sensitive compositions and their use BASF Aktiengesellschaft (DE) 1990-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028724-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS SLC43A3, SLC29A1, SLCO1A2 CYP1A2 1003/4885TSHR 4684/4885CASP1 3753/4885
US-20040013959-A1 Naphthalene tetracarboxylic diimide dimers INTS9, DHCR24, H1-0 CYP1A2 1018/4885TSHR 1374/4885CASP1 1017/4885
US-20050004365-A1 Naphthalene tetracarboxylic diimide dimers ALK, C9, AHR CYP1A2 288/4885TSHR 212/4885CASP1 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.