Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17057422 | 0.77 | TSHR (0.39) | TSHR | |
| SCHEMBL15014511 | 0.75 | SMN1; SMN2 (0.34) | SMN1; SMN2TSHR | |
| SCHEMBL19734244 | 0.75 | TSHR (0.32) | SMN1; SMN2TSHR | |
| SCHEMBL14067485 | 0.71 | NCF1 (0.30) | — | |
| SCHEMBL19734185 | 0.71 | NCF1 (0.30) | — | |
| SCHEMBL19734188 | 0.71 | NCF1 (0.30) | — | |
| SCHEMBL25045006 | 0.69 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL20970617 | 0.68 | TSHR (0.33) | TSHR | |
| SCHEMBL12523358 | 0.68 | TSHR (0.40) | SMN1; SMN2TSHR | |
| SCHEMBL21791310 | 0.67 | NAMPT (0.43) | SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362217-A1 | Substituted Piperidine Compounds | Epizyme, Inc. (US) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362217-A1 | Substituted Piperidine Compounds | SMYD3, SMYD2, SNRPD3 | SMN1; SMN2 40/4885TSHR 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.