Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24791130 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EGAAEPHX1EPHX2 | |
| SCHEMBL26893467 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EGAAEPHX1EPHX2 | |
| SCHEMBL7858206 | 0.73 | KDM4E (0.40) | SMN1; SMN2KDM4EGAAHSD11B1OPRM1 | |
| SCHEMBL29346750 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EGAAEPHX1EPHX2 | |
| SCHEMBL12464452 | 0.71 | KMT2A (0.44) | SMN1; SMN2KDM4EEPHX1EPHX2HSD11B1 | |
| SCHEMBL27373741 | 0.70 | NAMPT (0.43) | SMN1; SMN2KDM4EGAAEPHX1EPHX2 | |
| SCHEMBL21791310 | 0.70 | NAMPT (0.43) | SMN1; SMN2KDM4EGAAEPHX1EPHX2 | |
| SCHEMBL19734249 | 0.69 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL25125334 | 0.68 | KDM4E (0.38) | SMN1; SMN2KDM4EGAAEPHX1EPHX2 | |
| SCHEMBL24734696 | 0.68 | SMN1; SMN2 (0.37) | SMN1; SMN2EPHX1EPHX2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018648-A1 | PHENOL DERIVATIVES FOR USE IN THE MODULATION OF BRM | GENENTECH, INC. (US) | 2023-02-16 | — | — | WO | disclosed |