⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12128360 | 0.74 | — | — | |
| SCHEMBL30732357 | 0.74 | — | — | |
| SCHEMBL12125648 | 0.73 | CPN1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL25414494 | 0.72 | GNAO1 (0.37) | — | |
| SCHEMBL24009077 | 0.72 | SLC6A1 (0.35) | — | |
| SCHEMBL24701554 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL17220375 | 0.72 | GNAO1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL31700672 | 0.70 | SLC6A1 (0.34) | — | |
| SCHEMBL12128368 | 0.70 | GNAO1 (0.36) | — | |
| SCHEMBL20693761 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577363-B2 | Substituted piperidine compounds | Epizyme, Inc. (US) | 2020-03-03 | — | — | US | disclosed |
| US-20170362217-A1 | Substituted Piperidine Compounds | Epizyme, Inc. (US) | 2017-12-21 | — | — | US | disclosed |