Barbituric Acid

Barbituric Acid

SCHEMBL1973453

O=C1CC(=O)NC(=O)N1.[MgH2]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
CYP1A2 P05177 1/20 0.52
HPGD P15428 1/20 0.52
HIF1A Q16665 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CRBN Q96SW2 6/20 0.41
KDM4E B2RXH2 1/20 0.37
OGT O15294 1/20 0.37
USP2 O75604 1/20 0.37
MAPT P10636 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
ITGB3 P05106 1/20 0.36
ITGB1 P05556 1/20 0.36
ITGAV P06756 1/20 0.36
ITGA4 P13612 1/20 0.36
AHR P35869 5/20 0.35
PDK2 Q15119 1/20 0.35
TDP2 O95551 1/20 0.32
CASP3 P42574 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Barbituric Acid SCHEMBL9941322 0.96
Barbituric Acid SCHEMBL4560317 0.96 ALDH1A1 (0.55) ALDH1A1CYP1A2HPGDHIF1AHSD17B10
Barbituric Acid SCHEMBL38707 0.96
Barbituric Acid SCHEMBL1972516 0.93 ALDH1A1 (0.52) ALDH1A1CYP1A2HPGDHIF1AHSD17B10
Barbituric Acid SCHEMBL1973830 0.93 ALDH1A1 (0.52) ALDH1A1CYP1A2HPGDHIF1AHSD17B10
Barbituric Acid SCHEMBL11379882 0.93 ALDH1A1 (0.52) ALDH1A1CYP1A2HPGDHIF1AHSD17B10
Barbituric Acid SCHEMBL4278190 0.93 ALDH1A1 (0.52) ALDH1A1CYP1A2HPGDHIF1AHSD17B10
Barbituric Acid SCHEMBL1974368 0.93 ALDH1A1 (0.52) ALDH1A1CYP1A2HPGDHIF1AHSD17B10
Barbituric Acid SCHEMBL5924412 0.93 ALDH1A1 (0.52) ALDH1A1CYP1A2HPGDHIF1AHSD17B10
Barbituric Acid SCHEMBL4663533 0.90 ALDH1A1 (0.50) ALDH1A1CYP1A2HPGDHIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773459-B1 IMPROVED FLAME SUPPRESSANT AEROSOL GENERANT GOODRICH CORP (US) 2011-06-22 EP claimed
US-20080245537-A1 Flame suppressant aerosol generant GOODRICH CORPORATION 2008-10-09 US claimed
EP-1773459-A2 IMPROVED FLAME SUPPRESSANT AEROSOL GENERANT Universal Propulsion Company, Inc. (US) 2007-04-18 EP claimed
WO-2006052275-A2 IMPROVED FLAME SUPPRESSANT AEROSOL GENERANT UNIVERSAL PROPULSION COMPANY, INC. (US) 2006-05-18 WO claimed
US-20050242319-A1 Flame suppressant aerosol generant GOODRICH CORPORATION 2005-11-03 US claimed
US-10668311-B2 Fire suppressant inert gas generator GOODRICH CORPORATION (US) 2020-06-02 US disclosed
US-20200079707-A1 OBSCURANT EMISSION SYSTEMS AND METHODS GOODRICH CORPORATION (US) 2020-03-12 US disclosed
US-20190290952-A1 FIRE SUPPRESSANT INERT GAS GENERATOR GOODRICH CORPORATION (US) 2019-09-26 US disclosed
EP-3219365-B1 COMBUSTIBLE AEROSOL COMPOSITION GOODRICH CORP (US) 2018-10-31 EP disclosed
US-9994495-B2 Combustible aerosol composition GOODRICH CORPORATION (US) 2018-06-12 US disclosed
US-20180079695-A1 OBSCURANT EMISSION SYSTEMS AND METHODS GOODRICH CORPORATION (US) 2018-03-22 US disclosed
EP-3296280-A1 OBSCURANT EMISSION SYSTEMS AND METHODS Goodrich Corporation (US) 2018-03-21 EP disclosed
US-20110155943-A1 FLAME SUPPRESSANT AEROSOL GENERANT GOODRICH CORPORATION (US) 2011-06-30 US disclosed
EP-1773459-B1 IMPROVED FLAME SUPPRESSANT AEROSOL GENERANT GOODRICH CORP (US) 2011-06-22 EP disclosed
US-7906034-B2 Flame suppressant aerosol generant GOODRICH CORPORATION (US) 2011-03-15 US disclosed
US-20080245537-A1 Flame suppressant aerosol generant GOODRICH CORPORATION 2008-10-09 US disclosed
US-7407598-B2 Flame suppressant aerosol generant GOODRICH CORPORATION (US) 2008-08-05 US disclosed
EP-1773459-A2 IMPROVED FLAME SUPPRESSANT AEROSOL GENERANT Universal Propulsion Company, Inc. (US) 2007-04-18 EP disclosed
WO-2006052275-A2 IMPROVED FLAME SUPPRESSANT AEROSOL GENERANT UNIVERSAL PROPULSION COMPANY, INC. (US) 2006-05-18 WO disclosed
US-20050242319-A1 Flame suppressant aerosol generant GOODRICH CORPORATION 2005-11-03 US disclosed