Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29661763 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AALOX15CYP1A2 | |
| SCHEMBL12190764 | 0.82 | APP (0.37) | ALDH1A1MEN1KMT2AALOX15GAA | |
| SCHEMBL29661787 | 0.80 | APP (0.46) | ALDH1A1MEN1KMT2AALOX15GAA | |
| SCHEMBL12301896 | 0.80 | APP (0.46) | ALDH1A1MEN1KMT2AALOX15GAA | |
| SCHEMBL14044064 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ACYP1A2GAA | |
| SCHEMBL12375437 | 0.78 | SIGMAR1 (0.37) | ALDH1A1MEN1KMT2ALMNABTK | |
| SCHEMBL25455677 | 0.76 | STAT3 (0.31) | ALDH1A1MEN1KMT2AALOX15GAA | |
| SCHEMBL23540511 | 0.76 | HDAC1 (0.32) | ALDH1A1MEN1KMT2AALOX15GAA | |
| SCHEMBL931406 | 0.76 | HDAC1 (0.45) | ALDH1A1MEN1KMT2AALOX15CYP3A4 | |
| SCHEMBL23341752 | 0.76 | CXCR1 (0.40) | ALDH1A1MEN1KMT2AALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362226-A1 | RADIOACTIVE HALOGEN-LABELED PYRIDO [1,2-A] BENZIMIDAZOLE DERIVATIVE COMPOUND | KYOTO UNIVERSITY (JP) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362226-A1 | RADIOACTIVE HALOGEN-LABELED PYRIDO [1,2-A] BENZIMIDAZOLE DERIVATIVE COMPOUND | BRI3BP, BRD1, BRDT | ALDH1A1 168/4885MEN1 642/4885KMT2A 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.