Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19718001 | 0.88 | APLNR (0.54) | APLNR | |
| SCHEMBL19717995 | 0.75 | APLNR (0.58) | APLNR | |
| SCHEMBL19717898 | 0.73 | APLNR (0.60) | APLNR | |
| SCHEMBL20584774 | 0.68 | APLNR (0.67) | APLNR | |
| SCHEMBL19718039 | 0.68 | APLNR (0.54) | APLNR | |
| SCHEMBL19717937 | 0.67 | APLNR (0.64) | APLNR | |
| SCHEMBL23722264 | 0.66 | APLNR (1.00) | APLNR | |
| SCHEMBL19403057 | 0.65 | APLNR (0.62) | APLNR | |
| SCHEMBL19405040 | 0.64 | APLNR (0.61) | APLNR | |
| SCHEMBL23048510 | 0.64 | APLNR (0.61) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017218633-A1 | 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONE AS APJ AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-21 | — | — | WO | disclosed |