Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | XDH | P47989 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | KDM1A | O60341 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382208 | 0.93 | CYP19A1 (0.62) | CYP19A1MAPTTP53CYP3A4XDH | |
| SCHEMBL16894660 | 0.89 | ODC1 (0.50) | CYP19A1MAPTABCG2PTPN1POLB | |
| SCHEMBL2124058 | 0.85 | CYP19A1 (0.68) | CYP19A1MAPTTP53CYP3A4XDH | |
| SCHEMBL14829728 | 0.85 | CYP19A1 (0.65) | CYP19A1MAPTTP53CYP3A4XDH | |
| SCHEMBL12878874 | 0.85 | CYP19A1 (0.65) | CYP19A1MAPTTP53CYP3A4XDH | |
| SCHEMBL2319144 | 0.85 | CYP19A1 (0.68) | CYP19A1MAPTTP53CYP3A4XDH | |
| SCHEMBL16894664 | 0.84 | MAOB (0.60) | CYP19A1MAPTCYP3A4NPC1RAB9A | |
| SCHEMBL10425232 | 0.84 | ABCG2 (0.60) | CYP19A1MAPTCYP3A4HPGDNPC1 | |
| SCHEMBL16894614 | 0.84 | PTAFR (0.49) | CYP19A1MAPTCYP3A4HPGDALDH1A1 | |
| SCHEMBL30674790 | 0.83 | MAOB (0.57) | CYP19A1MAPTCYP3A4HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170360744-A1 | AGENT CONTAINING FLAVONOID DERIVATIVES FOR TREATING CANCER AND INFLAMMATION | FLAVOCURE BIOTECH INC. | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360744-A1 | AGENT CONTAINING FLAVONOID DERIVATIVES FOR TREATING CANCER AND INFLAMMATION | TNF, NLRP3, F3 | CYP19A1 78/4885MAPT 1505/4885TP53 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.