Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.80 |
| ▸ | AKR1B1 | P15121 | 10/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.69 |
| ▸ | MMP3 | P08254 | 3/20 | 0.69 |
| ▸ | MMP13 | P45452 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.68 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.59 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408642 | 0.89 | PKM (1.00) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL19736089 | 0.89 | PKM (1.00) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL29408612 | 0.87 | PKM (0.78) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL19736229 | 0.87 | PKM (0.78) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL19736244 | 0.83 | MEN1 (0.66) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL29408614 | 0.83 | MEN1 (0.66) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL15863399 | 0.82 | AKR1B1 (1.00) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL15869598 | 0.82 | AKR1B1 (1.00) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL15863400 | 0.82 | AKR1B1 (1.00) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL10492239 | 0.81 | MAPT (0.79) | AKR1B1PTPN1MMP3MMP13PTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017215552-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS FOR USE THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2017-12-21 | — | — | WO | disclosed |