Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 9/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.70 |
| ▸ | MMP3 | P08254 | 3/20 | 0.70 |
| ▸ | MMP13 | P45452 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.69 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.60 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19736089 | 1.00 | PKM (1.00) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL21450817 | 0.89 | PKM (0.80) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL19736090 | 0.89 | PKM (0.80) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL29408612 | 0.88 | PKM (0.78) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL19736229 | 0.88 | PKM (0.78) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL15863399 | 0.83 | AKR1B1 (1.00) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL15863400 | 0.83 | AKR1B1 (1.00) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL15869598 | 0.83 | AKR1B1 (1.00) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL29408630 | 0.82 | PKM (0.69) | PKMAKR1B1PTPN1MMP3MMP13 | |
| SCHEMBL19736165 | 0.82 | PKM (0.69) | PKMAKR1B1PTPN1MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220378751-A1 | INHIBITING DIHYDROFOLATE REDUCTASE IN A MICROORGANISM | VERSITECH LIMITED (HK) | 2022-12-01 | — | — | US | disclosed |
| CN-109414432-B | Antimicrobial compounds and methods of use thereof | 港大科桥有限公司 | 2022-03-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220378751-A1 | INHIBITING DIHYDROFOLATE REDUCTASE IN A MICROORGANISM | DHFR, BLVRB, QDPR | PKM 2019/4885AKR1B1 92/4885PTPN1 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.