Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | SLC6A12 | P48065 | 5/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035897 | 1.00 | AKR1C4 (0.53) | AKR1C4AKR1C3AKR1C2SLC6A12SLC6A11 | |
| SCHEMBL12189850 | 0.82 | AKR1C4 (0.37) | AKR1C4AKR1C3AKR1C2TLR4 | |
| SCHEMBL10053664 | 0.81 | AKR1C4 (0.40) | AKR1C4AKR1C3AKR1C2TLR4TDP1 | |
| SCHEMBL13523241 | 0.79 | AKR1C4 (0.36) | AKR1C4AKR1C3AKR1C2TLR4MAPT | |
| SCHEMBL19736432 | 0.79 | BRD4 (0.39) | AKR1C4AKR1C3AKR1C2TLR4TSHR | |
| SCHEMBL14468370 | 0.79 | BRD4 (0.39) | AKR1C4AKR1C3AKR1C2TLR4TSHR | |
| SCHEMBL14305274 | 0.77 | — | — | |
| SCHEMBL11863746 | 0.74 | AKR1C4 (0.68) | AKR1C4AKR1C3AKR1C2SLC6A12SLC6A11 | |
| SCHEMBL10053671 | 0.74 | AKR1C4 (0.33) | AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL11989050 | 0.73 | AKR1C4 (0.33) | AKR1C4AKR1C3AKR1C2TLR4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746401-B | Ionizable lipids for nucleic acid delivery | 精密纳米系统无限责任公司 | 2023-12-08 | — | — | CN | disclosed |
| US-20220396548-A1 | IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY | GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) | 2022-12-15 | — | — | US | disclosed |
| CN-114746401-A | Ionizable lipids for nucleic acid delivery | 精密纳米系统有限公司 | 2022-07-12 | — | — | CN | disclosed |
| EP-3986866-A1 | IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY | Precision Nanosystems Inc (CA) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020252589-A1 | IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY | Precision Nanosystems Inc. (CA) | 2020-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220396548-A1 | IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY | RNASEH1, NSUN3, SLC67A1 | AKR1C4 3810/4885AKR1C3 3622/4885AKR1C2 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.