Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.36 |
| ▸ | CDK2 | P24941 | 9/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | TAF1 | P21675 | 2/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19736506 | 0.94 | FDPS (0.40) | ACACBFDPSCNR2MAPTGSK3B | |
| SCHEMBL19736465 | 0.92 | CBLB (0.38) | ACACBBRD4PLK1MAPTGSK3B | |
| SCHEMBL19713928 | 0.92 | RPS6KB1 (0.34) | ACACBCCNE1CDK2MAPTGSK3B | |
| SCHEMBL19713930 | 0.92 | RPS6KB1 (0.34) | ACACBCCNE1CDK2MAPTGSK3B | |
| SCHEMBL19736179 | 0.90 | HRH3 (0.37) | ACACBFDPSCNR2MAPTGSK3B | |
| SCHEMBL22239575 | 0.90 | MAP3K12 (0.36) | ACACBFDPSCNR2MAPTGSK3B | |
| SCHEMBL19736178 | 0.90 | CNR2 (0.37) | ACACBFDPSCNR2MAPTGSK3B | |
| SCHEMBL19736513 | 0.90 | ACACB (0.38) | ACACBFDPSCNR2MAPTGSK3B | |
| SCHEMBL17777114 | 0.90 | ACACB (0.39) | ACACBFDPSMAPTGSK3B | |
| SCHEMBL19714521 | 0.89 | GSK3B (0.37) | CCNE1CDK2MAPTGSK3BPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362234-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-12-21 | — | — | US | disclosed |
| US-9214258-B2 | Semiconductor composites comprising carbon nanotubes and diketopyrrolopyrrole-thiophene based copolymers | XEROX CORPORATION (US) | 2015-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362234-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | SIRT1, SIRT3, SIRT2 | ACACB 306/4885CCNE1 1954/4885CDK2 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.