Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19737027 | 0.95 | TSHR (0.30) | TSHR | |
| SCHEMBL19736676 | 0.90 | — | — | |
| SCHEMBL19737031 | 0.89 | — | — | |
| SCHEMBL19737032 | 0.85 | — | — | |
| SCHEMBL19736891 | 0.84 | — | — | |
| SCHEMBL19736889 | 0.84 | — | — | |
| SCHEMBL19736762 | 0.79 | ALDH1A1 (0.34) | ALOX15 | |
| SCHEMBL19736671 | 0.79 | TSHR (0.34) | TSHRALOX15 | |
| SCHEMBL19737023 | 0.77 | — | — | |
| SCHEMBL19736662 | 0.75 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345653-B2 | Compositions and methods for reactivating cholinesterases | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE INC. (US) | 2022-05-31 | — | — | US | disclosed |
| US-20190345097-A1 | Compositions and Methods for Reactivating Cholinesterases | The Henry M. Jackson Foundation for the Advancemen t of Military Medicine, Inc. (US) | 2019-11-14 | — | — | US | disclosed |
| WO-2017218886-A1 | COMPOSITIONS AND METHODS FOR REACTIVATING CHOLINESTERASES | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2017-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345653-B2 | Compositions and methods for reactivating cholinesterases | ACHE, BCHE, CHAT | TSHR 3268/4885ALOX15 1916/4885 |
| US-20190345097-A1 | Compositions and Methods for Reactivating Cholinesterases | ACHE, BCHE, CHAT | TSHR 3268/4885ALOX15 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.