Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973757 | 0.91 | ALDH1A1 (0.46) | EPHX2MEN1ALDH1A1LMNAALPL | |
| SCHEMBL1972817 | 0.87 | EPHX2 (0.42) | EPHX2ALDH1A1P2RX7 | |
| SCHEMBL1975578 | 0.80 | P2RX7 (0.39) | EPHX2P2RX7 | |
| SCHEMBL12427407 | 0.80 | ALDH1A1 (0.53) | EPHX2ALDH1A1LMNAP2RX7 | |
| SCHEMBL1972816 | 0.79 | ALDH1A1 (0.45) | EPHX2ALDH1A1 | |
| SCHEMBL12427409 | 0.78 | KCNH2 (0.55) | EPHX2MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL12427384 | 0.78 | ALDH1A1 (0.47) | EPHX2ALDH1A1HTT | |
| SCHEMBL965846 | 0.77 | SLC22A2 (0.48) | EPHX2ALDH1A1P2RX7 | |
| SCHEMBL1006767 | 0.76 | ALDH1A1 (0.48) | ALDH1A1LMNAP2RX7 | |
| SCHEMBL12427348 | 0.76 | KCNH2 (0.51) | MEN1ALDH1A1LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994020-B1 | Substituted quinolones III | AICURIS GMBH & CO KG (DE) | 2011-06-22 | — | — | EP | disclosed |