Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29477241 | 0.73 | LMNA (0.50) | MAPK1 | |
| SCHEMBL24724928 | 0.73 | GRM2 (0.36) | — | |
| SCHEMBL17149930 | 0.71 | — | — | |
| SCHEMBL19738027 | 0.69 | — | — | |
| SCHEMBL25148063 | 0.65 | CCNK (0.36) | MAPK1 | |
| SCHEMBL20743311 | 0.64 | KMT2A (0.33) | — | |
| SCHEMBL14158421 | 0.61 | DYRK1A (0.40) | — | |
| SCHEMBL20548194 | 0.58 | — | — | |
| SCHEMBL8141395 | 0.57 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL12102965 | 0.57 | MAPK1 (0.53) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017218960-A1 | HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2017-12-21 | — | — | WO | disclosed |