Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15710231 | 0.76 | MAPK1 (0.44) | GRM2L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL19738044 | 0.73 | MAPK1 (0.31) | — | |
| SCHEMBL16502349 | 0.73 | GRM2 (0.37) | GRM2L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL14838548 | 0.72 | GRM2 (0.46) | GRM2L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL1491074 | 0.72 | KDM4E (0.47) | GRM2L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL22303574 | 0.71 | CNR2 (0.41) | GRM2L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL23188013 | 0.71 | MAPT (0.40) | GRM2L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL12881335 | 0.70 | GRM2 (0.36) | GRM2L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL6154196 | 0.69 | MAPK1 (0.42) | GRM2L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL14858192 | 0.69 | MAPT (0.42) | GRM2L3MBTL1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |