Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17982706 | 0.85 | EPHX1 (0.43) | KMT2AEPHX1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL17956788 | 0.82 | EPHX1 (0.45) | KMT2AEPHX1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL19741226 | 0.79 | EPHX1 (0.45) | EPHX1ALDH1A1SIGMAR1CYP3A4NPC1 | |
| SCHEMBL17956777 | 0.77 | SIGMAR1 (0.45) | EPHX1ALDH1A1KDM4ESIGMAR1CYP3A4 | |
| SCHEMBL11529346 | 0.76 | HTT (0.53) | KMT2AALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL7560180 | 0.76 | KMT2A (0.51) | KMT2AEPHX1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL17956791 | 0.76 | ALDH1A1 (0.37) | KMT2AEPHX1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL31349955 | 0.75 | EPHX1 (0.43) | EPHX1ALDH1A1KDM4ESIGMAR1CYP3A4 | |
| SCHEMBL6577782 | 0.74 | SIGMAR1 (0.49) | KMT2AEPHX1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL19741335 | 0.73 | SIGMAR1 (0.42) | EPHX1ALDH1A1KDM4ESIGMAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10767112-B2 | Methods of producing metal sulfides, metal selenides, and metal sulfides/selenides having controlled architectures using kinetic control | THE TRUSTEES OF THE COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-09-08 | — | — | US | disclosed |
| US-20170369779-A1 | METHODS OF PRODUCING METAL SULFIDES, METAL SELENIDES, AND METAL SULFIDES/SELENIDES HAVING CONTROLLED ARCHITECTURES USING KINETIC CONTROL | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-12-28 | — | — | US | disclosed |