SCHEMBL19741576

SCHEMBL19741576

C[Si](C)(O[Si](c1ccccc1)(c1ccccc1)c1ccccc1)O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
CA4 P22748 1/20 0.32
MAPT P10636 1/20 0.31
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392326 0.97 ESR1 (0.38) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL5552262 0.93 ESR1 (0.35) ESR1ESR2
SCHEMBL3154426 0.91 ESR1 (0.34) ESR1ESR2
SCHEMBL8763804 0.91 ESR1 (0.34) ESR1ESR2
SCHEMBL18094247 0.87 ESR1 (0.32) ESR1ESR2CA4
SCHEMBL2048191 0.84 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL13621322 0.84 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL15949975 0.84 ESR1 (0.31) ESR1ESR2
SCHEMBL15950038 0.84 ESR1 (0.31) ESR1ESR2
SCHEMBL15950037 0.84 ESR1 (0.31) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458499-B1 FLAME RETARDANT RESIN COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2026-03-25 EP disclosed
US-20240247107-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2024-07-25 US disclosed
EP-4347702-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2024-04-10 EP disclosed
WO-2022253413-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2022-12-08 WO disclosed
CN-109642029-B Flame-retardant resin composition 莫门蒂夫性能材料股份有限公司 2022-02-18 CN disclosed
US-10266648-B2 Flame retardant resin composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-04-23 US disclosed
US-20170369644-A1 FLAME RETARDANT RESIN COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2017-12-28 US disclosed
US-20170369644-A1 FLAME RETARDANT RESIN COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2017-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10266648-B2 Flame retardant resin composition RER1, GAR1, AFF1 ESR1 1082/4885ESR2 836/4885NR1H2 425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.