Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19741746 | 1.00 | ACE (0.44) | ACELMNADPP4ALDH1A1HPGD | |
| SCHEMBL17143980 | 1.00 | ACE (0.44) | ACELMNADPP4ALDH1A1HPGD | |
| SCHEMBL17143978 | 1.00 | ACE (0.44) | ACELMNADPP4ALDH1A1HPGD | |
| SCHEMBL17144390 | 0.93 | CTSL (0.41) | LMNAALDH1A1HPGDCTSLCTSB | |
| SCHEMBL17144595 | 0.93 | CTSL (0.41) | LMNAALDH1A1HPGDCTSLCTSB | |
| SCHEMBL19741667 | 0.91 | TACR1 (0.40) | ACELMNAALDH1A1TACR1HSD11B1 | |
| SCHEMBL19741669 | 0.91 | TACR1 (0.40) | ACELMNAALDH1A1TACR1HSD11B1 | |
| SCHEMBL19741670 | 0.91 | TACR1 (0.40) | ACELMNAALDH1A1TACR1HSD11B1 | |
| SCHEMBL29865958 | 0.84 | TACR1 (0.41) | ALDH1A1CTSLCTSBCTSKTACR1 | |
| SCHEMBL17145089 | 0.80 | ACE (0.49) | ACEALDH1A1HPGDHSD11B1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | KDM1B, KDM3A, KDM1A | ACE 3020/4885LMNA 2625/4885DPP4 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.