Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19741670 | 1.00 | TACR1 (0.40) | TACR1MEN1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL19741667 | 1.00 | TACR1 (0.40) | TACR1MEN1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL29865958 | 0.94 | TACR1 (0.41) | TACR1MEN1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL19741745 | 0.91 | ACE (0.44) | TACR1ALDH1A1HSD11B1ACELMNA | |
| SCHEMBL19741746 | 0.91 | ACE (0.44) | TACR1ALDH1A1HSD11B1ACELMNA | |
| SCHEMBL17143978 | 0.91 | ACE (0.44) | TACR1ALDH1A1HSD11B1ACELMNA | |
| SCHEMBL17143980 | 0.91 | ACE (0.44) | TACR1ALDH1A1HSD11B1ACELMNA | |
| SCHEMBL17144595 | 0.84 | CTSL (0.41) | TACR1KMT2AALDH1A1HSD11B1LMNA | |
| SCHEMBL17144390 | 0.84 | CTSL (0.41) | TACR1KMT2AALDH1A1HSD11B1LMNA | |
| SCHEMBL17145035 | 0.80 | HSD11B1 (0.45) | MEN1KMT2AALDH1A1HSD11B1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | KDM1B, KDM3A, KDM1A | TACR1 4648/4885MEN1 3018/4885KMT2A 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.