SCHEMBL197418

SCHEMBL197418

CCC(=O)Oc1ccc(Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.63
ESR1 P03372 2/20 0.63
HIF1A Q16665 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
RECQL P46063 1/20 0.63
ELANE P08246 2/20 0.58
ACHE P22303 2/20 0.49
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
MAPT P10636 2/20 0.48
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
CYP1A2 P05177 3/20 0.47
CYP2C19 P33261 2/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 2/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
GLA P06280 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9799923 1.00 KMT2A (0.63) KMT2AESR1HIF1ASMN1; SMN2RECQL
Hydrochloric Acid SCHEMBL23467129 0.98 KMT2A (0.61) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL8582397 0.94 KMT2A (0.58) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL312147 0.89 KMT2A (0.76) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL11445596 0.87 KMT2A (0.73) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL5468900 0.84 BCL9 (0.60) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL1244295 0.83 KMT2A (0.54) KMT2ASMN1; SMN2ELANEALDH1A1HSD17B10
SCHEMBL643983 0.83 KMT2A (0.63) KMT2AELANEALDH1A1HSD17B10MAPT
SCHEMBL9171166 0.83 KMT2A (0.68) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL6282777 0.83 KMT2A (0.68) KMT2AESR1HIF1ASMN1; SMN2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104388516-A Preparation of (R)-(+)-3-chloro-1-phenylpropan-1-ol WANG TONGJUN 2015-03-04 CN claimed
CN-104388480-A Synthesis and use of R-1-phenylethyl esters WANG TONGJUN 2015-03-04 CN claimed
CN-102321034-A Sulfobenzodiazepine compound and application thereof used as medicament UNIV PLA 2ND MILITARY MEDICAL 2012-01-18 CN claimed
CN-101909451-A Fungicidal mixtures II BASF SE 2010-12-08 CN claimed
CN-101380317-A Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV (CN) 2009-03-11 CN claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
CN-120157577-A Application of tetra-n-butyl ammonium bromide as catalyst in catalyzing reaction of methoxyl aromatic hydrocarbon and acyl bromide 皖南医学院 2025-06-17 CN disclosed
EP-4455159-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS WITH BIO-DISTRIBUTION MODIFIER 3B Pharmaceuticals GmbH (DE) 2024-10-30 EP disclosed
CN-118666764-A Triazole amide compound, preparation method and application thereof 中国人民解放军海军军医大学 2024-09-20 CN disclosed
CN-118304468-A Supermolecule medical material capable of regulating cell behavior 北京理工大学 2024-07-09 CN disclosed
CN-117263778-A Preparation method of styrene series compound for 248nm photoresist 河北凯诺中星科技有限公司 2023-12-22 CN disclosed
EP-4222151-A1 ALPHA PROTEIN KINASE 1 INHIBITORS AND METHODS OF USE Shanghai Yao Yuan Biotechnology Co., Ltd. (CN) 2023-08-09 EP disclosed
EP-4170347-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2023-04-26 EP disclosed
CN-88102069-A The indazole insecticides that replaces 1988-10-26 CN disclosed
WO-1988007994-A1 INSECTICIDAL SUBSTITUTED INDAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-10-20 WO disclosed
EP-0286346-A2 Insecticidal substituted indazoles E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-10-12 EP disclosed
US-4759789-A Treating locus of plant before or during application of herbicide with oxime ether compound CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
EP-0234242-A2 Fungicidal azolyl-derivatives MONTEDIPE S.r.l. (IT) 1987-09-02 EP disclosed
US-4566901-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-01-28 US disclosed
EP-0094348-A1 Oxime ethers, process for their preparation, agents containing the oxime ethers and their use CIBA-GEIGY AG (CH) 1983-11-16 EP disclosed