SCHEMBL643983

SCHEMBL643983

O=C(CCC(=O)Oc1ccc(Cl)cc1)Oc1ccc(Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.63
MAPT P10636 2/20 0.63
ALDH1A1 P00352 1/20 0.63
LMNA P02545 1/20 0.63
HTT P42858 1/20 0.63
HSD17B10 Q99714 1/20 0.63
TDP1 Q9NUW8 1/20 0.55
ELANE P08246 1/20 0.46
TAAR1 Q96RJ0 1/20 0.45
LIPE Q05469 2/20 0.44
BCL9 O00512 1/20 0.44
CTNNB1 P35222 1/20 0.44
TSHR P16473 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HPGD P15428 1/20 0.44
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19690545 0.92 KMT2A (0.55) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL10502576 0.91 KMT2A (0.61) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL11804399 0.91 KMT2A (0.60) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL11654682 0.88 KMT2A (0.50) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL5468900 0.88 BCL9 (0.60) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL27514586 0.87 KMT2A (0.55) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL28782938 0.87 KMT2A (0.50) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL1244295 0.86 KMT2A (0.54) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL189948 0.86 KMT2A (0.56) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL4671096 0.86 KMT2A (0.55) KMT2AMAPTALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115109430-A Pigment and preparation method thereof 宁夏彩妍科技有限公司 2022-09-27 CN claimed
CN-114716591-B Catalyst component for propylene polymerization, preparation method and application thereof 任丘市利和科技发展有限公司 2024-05-28 CN disclosed
CN-115109430-A Pigment and preparation method thereof 宁夏彩妍科技有限公司 2022-09-27 CN disclosed
EP-2723750-B1 DIKETOPYRROLOPYRROLE OLIGOMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES CLAP CO LTD (KR) 2022-08-10 EP disclosed
EP-2751855-B1 DIKETOPYRROLOPYRROLE OLIGOMERS AND COMPOSITIONS, COMPRISING DIKETOPYRROLOPYRROLE OLIGOMERS BASF SE (DE) 2020-10-28 EP disclosed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 US disclosed
EP-2216312-B1 PROCESS FOR PRODUCING ORGANIC COMPOUND M TECHNIQUE CO LTD (JP) 2019-05-01 EP disclosed
EP-2236562-B1 PIGMENT COMPOSITION FOR RED COLOR FILTER, METHOD FOR PRODUCING THE SAME, COLOR COMPOSITION USING THE SAME, AND COLOR FILTER TOYO INK MFG CO (JP) 2018-10-10 EP disclosed
CN-108570120-A Ingredient of solid catalyst and catalyst containing o-phenylenediamine class compound and its application 北京利和知信科技有限公司 2018-09-25 CN disclosed
CN-108570119-A A kind of ingredient of solid catalyst containing naphthylenediamine class compound, catalyst and its application 北京利和知信科技有限公司 2018-09-25 CN disclosed
US-20020010331-A1 Reacting succinic diester with nitrile CLARIANT GMBH 2002-01-24 US disclosed
CN-1066766-C Diketopyrrolopyrrole pigment with high chroma CIBA SC HOLDING AG (CH) 2001-06-06 CN disclosed
US-6057449-A HEATING A DISUCCINATE WITH A NITRILE IN THE PRESENCE OF BASE CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-02 US disclosed
EP-0962499-A2 Direct preparation of pigmentary pyrrolo-(3,4-C)pyrroles Ciba SC Holding AG (CH) 1999-12-08 EP disclosed
US-5492564-A HIGH OPACITY, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1996-02-20 US disclosed
CN-1113251-A Diketopyrrolopyrrole pigment with high chroma CIBA GEIGY AG (CH) 1995-12-13 CN disclosed
US-4749795-A Phenyl substituted pyrrolinones CIBA-GEIGY CORPORATION (US) 1988-06-07 US disclosed
US-4720305-A Mixtures of pigments CIBA-GEIGY CORPORATION (US) 1988-01-19 US disclosed
US-4681971-A Phenyl substituted aminodicarboxylate esters CIBA-GEIGY CORPORATION (US) 1987-07-21 US disclosed
US-4579949-A REACTING DISUCCINATE WITH NITRILES CIBA-GEIGY CORPORATION (US) 1986-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010331-A1 Reacting succinic diester with nitrile SDHA, QDPR, SDHB KMT2A 2122/4885MAPT 2253/4885ALDH1A1 790/4885
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B KMT2A 2142/4885MAPT 2703/4885ALDH1A1 2055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.