Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | WRN | Q14191 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3280851 | 0.89 | APP (0.46) | SMN1; SMN2APPTP53ESR1ESR2 | |
| SCHEMBL9968693 | 0.84 | APP (0.55) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL18015719 | 0.83 | TP53 (0.56) | APPTP53HSD17B1HSD17B2ESR1 | |
| SCHEMBL1105468 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2APPTP53WRNIKBKB | |
| SCHEMBL2493917 | 0.82 | IDO1 (0.48) | SMN1; SMN2TP53IDO1ALDH1A1EGFR | |
| SCHEMBL12575567 | 0.82 | APP (0.52) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL17678539 | 0.82 | APP (0.47) | SMN1; SMN2APPTP53HSD17B1HSD17B2 | |
| SCHEMBL14003448 | 0.80 | CYP3A4 (0.40) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL13197660 | 0.80 | CYP3A4 (0.40) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL10332066 | 0.79 | CYP2E1 (0.42) | SMN1; SMN2APPHSD17B1HSD17B2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | CRY1, NR2E3, LEF1 | SMN1; SMN2 3563/4885APP 2592/4885TP53 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.