Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 19/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.56 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.54 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.54 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.54 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19742469 | 1.00 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742467 | 1.00 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742449 | 0.91 | CSNK2A2 (0.54) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742448 | 0.91 | CSNK2A2 (0.54) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742440 | 0.89 | CSNK2A2 (0.59) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742422 | 0.88 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742733 | 0.87 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742433 | 0.87 | KCNH2 (0.65) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742577 | 0.87 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL29355651 | 0.87 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3474855-B1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS INC (US) | 2022-01-26 | — | — | EP | claimed |
| EP-3474855-A1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | Polaris Pharmaceuticals, Inc. (US) | 2019-05-01 | — | — | EP | claimed |
| US-10227344-B2 | CK2 inhibitors, compositions and methods thereof | POLARIS PHARMACEUTICALS, INC. (US) | 2019-03-12 | — | — | US | claimed |
| WO-2017223432-A1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS (US) | 2017-12-28 | — | — | WO | claimed |
| US-20170369489-A1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS | 2017-12-28 | — | — | US | claimed |
| EP-3474855-B1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS INC (US) | 2022-01-26 | — | — | EP | disclosed |
| EP-3474855-A1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | Polaris Pharmaceuticals, Inc. (US) | 2019-05-01 | — | — | EP | disclosed |
| US-10227344-B2 | CK2 inhibitors, compositions and methods thereof | POLARIS PHARMACEUTICALS, INC. (US) | 2019-03-12 | — | — | US | disclosed |
| WO-2017223432-A1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS (US) | 2017-12-28 | — | — | WO | disclosed |
| US-20170369489-A1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369489-A1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | CSNK1A1, CSNK2A1, CSNK2A3 | CSNK2A2 4/4885CSNK2A1 2/4885CSNK2B 11/4885 |
| US-10227344-B2 | CK2 inhibitors, compositions and methods thereof | CSNK1A1, CSNK2A1, CSNK2A3 | CSNK2A2 4/4885CSNK2A1 2/4885CSNK2B 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.