Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603114 | 0.82 | TSHR (0.60) | TSHRFAAHALDH1A1CNR1CNR2 | |
| SCHEMBL9402683 | 0.81 | TSHR (0.51) | TSHRFAAHALDH1A1THRBPOLB | |
| SCHEMBL441439 | 0.81 | FAAH (0.47) | TSHRFAAHALDH1A1CNR1CNR2 | |
| SCHEMBL5079277 | 0.79 | FAAH (0.54) | TSHRFAAHALDH1A1CNR1CNR2 | |
| SCHEMBL3682218 | 0.79 | TSHR (0.53) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL8927245 | 0.79 | TSHR (0.49) | TSHRFAAHPOLBAPEX1HTT | |
| SCHEMBL19614589 | 0.78 | FAAH (0.57) | TSHRFAAHALDH1A1CNR1CNR2 | |
| SCHEMBL2312371 | 0.78 | FAAH (0.57) | TSHRFAAHALDH1A1CNR1CNR2 | |
| SCHEMBL1138701 | 0.78 | FAAH (0.57) | TSHRFAAHALDH1A1CNR1CNR2 | |
| SCHEMBL11195272 | 0.78 | FAAH (0.57) | TSHRFAAHALDH1A1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369728-A1 | METHOD OF FORMING A PASSIVATED PIGMENT SLURRY FOR AN AQUEOUS TOPCOAT COATING COMPOSITION | BASF CORPORATION | 2017-12-28 | — | — | US | disclosed |