Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979276 | 0.89 | CCR1 (0.49) | CCR1CCR5CCR8PDE4BNOS1 | |
| SCHEMBL198406 | 0.75 | CCR1 (0.54) | CCR1CCR5CCR8NOS1NOS2 | |
| SCHEMBL196913 | 0.74 | CCR1 (0.83) | CCR1CCR5CCR8NOS1NOS2 | |
| SCHEMBL182529 | 0.71 | CCR1 (1.00) | CCR1CCR5CCR8NOS1NOS2 | |
| SCHEMBL29395249 | 0.71 | CCR1 (1.00) | CCR1CCR5CCR8NOS1NOS2 | |
| SCHEMBL2536198 | 0.70 | CCR1 (0.63) | CCR1CCR5CCR8NOS1NOS2 | |
| SCHEMBL31010071 | 0.70 | KAT7 (0.50) | PDE4BNOS1NOS3HTTMAPT | |
| SCHEMBL5792386 | 0.70 | MEN1 (0.59) | PDE4BHTTMAPTUSP2GAA | |
| SCHEMBL30046633 | 0.70 | MEN1 (0.59) | PDE4BHTTMAPTUSP2GAA | |
| Methane SCHEMBL21386924 | 0.69 | CCR1 (0.95) | CCR1CCR5CCR8NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180128767-A1 | Small Volume In Vitro Analyte Sensor | ABBOTT DIABETES CARE INC. (US) | 2018-05-10 | — | — | US | disclosed |
| US-9891185-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2018-02-13 | — | — | US | disclosed |
| US-9662057-B2 | Integrated sample acquisition and analyte measurement method | ABBOTT DIABETES CARE INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160334356-A1 | Small Volume In Vitro Analyte Sensor | THERASENSE, INC. | 2016-11-17 | — | — | US | disclosed |
| US-20160235350-A1 | Integrated Sample Acquisition and Analyte Measurement Device | THERASENSE, INC. | 2016-08-18 | — | — | US | disclosed |
| US-9341591-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9316609-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9291592-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-9271669-B2 | Method for integrated sample acquisition and analyte measurement device | ABBOTT DIABETES CARE INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-9234863-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-20040054267-A1 | Small volume in vitro analyte sensor | THERASENSE, INC. | 2004-03-18 | — | — | US | disclosed |
| US-20030199744-A1 | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator | THERASENSE, INC. (US) | 2003-10-23 | — | — | US | disclosed |
| US-6618934-B1 | Method of manufacturing small volume in vitro analyte sensor | THERASENSE, INC. | 2003-09-16 | — | — | US | disclosed |
| US-6592745-B1 | Analytical sensors for the detection of bioanalytes in a small volume sample; to monitor glucose in diabetic patients and lactate during critical care | THERASENSE, INC. | 2003-07-15 | — | — | US | disclosed |
| US-6591125-B1 | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator | THERASENSE, INC. | 2003-07-08 | — | — | US | disclosed |
| US-6461496-B1 | BLOOD GLUCOSE | THERASENSE, INC. | 2002-10-08 | — | — | US | disclosed |
| US-6338790-B1 | DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE | THERASENSE, INC. | 2002-01-15 | — | — | US | disclosed |
| US-6299757-B1 | ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS | THERASENSE, INC. | 2001-10-09 | — | — | US | disclosed |
| EP-1119637-A1 | SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR | Therasense, Inc. (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020626-A1 | SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR | THERASENSE, INC. (US) | 2000-04-13 | — | — | WO | disclosed |