Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197433 | 0.89 | CCR1 (0.50) | CCR1CCR5CCR8LMNAHTR1A | |
| SCHEMBL198406 | 0.74 | CCR1 (0.54) | CCR1CCR5CCR8NOS1NOS2 | |
| SCHEMBL196913 | 0.73 | CCR1 (0.83) | CCR1CCR5CCR8HTR1ANOS1 | |
| SCHEMBL27874761 | 0.72 | SIGMAR1 (0.57) | LMNAKMT2APOLB | |
| SCHEMBL182529 | 0.70 | CCR1 (1.00) | CCR1CCR5CCR8NOS1NOS2 | |
| SCHEMBL29395249 | 0.70 | CCR1 (1.00) | CCR1CCR5CCR8NOS1NOS2 | |
| SCHEMBL2536198 | 0.70 | CCR1 (0.63) | CCR1CCR5CCR8LMNANOS1 | |
| SCHEMBL8746042 | 0.68 | CCR1 (0.95) | CCR1CCR5CCR8NOS1NOS2 | |
| Methane SCHEMBL21386924 | 0.68 | CCR1 (0.95) | CCR1CCR5CCR8NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL29903189 | 0.68 | CCR1 (0.95) | CCR1CCR5CCR8NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8449758-B2 | Small volume in vitro analyte sensor and methods of making | ABBOTT DIABETES CARE INC. (US) | 2013-05-28 | — | — | US | disclosed |
| US-8083924-B2 | Small volume in vitro analyte sensor and methods of making | ABBOTT DIABETES CARE INC. (US) | 2011-12-27 | — | — | US | disclosed |