SCHEMBL19743776

SCHEMBL19743776

CN(C)CCNc1ccc(F)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 1/20 0.54
MEN1 O00255 2/20 0.50
POLB P06746 2/20 0.50
BLM P54132 2/20 0.50
KMT2A Q03164 2/20 0.50
NSD2 O96028 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
BRCA1 P38398 1/20 0.49
HIF1A Q16665 1/20 0.49
TOP2B Q02880 3/20 0.49
EHMT2 Q96KQ7 5/20 0.47
NPC1 O15118 1/20 0.47
MTOR P42345 1/20 0.47
RAB9A P51151 1/20 0.47
SIRT2 Q8IXJ6 1/20 0.47
TOP1 P11387 1/20 0.44
ALDH1A1 P00352 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
EGFR P00533 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20482316 0.92 SMN1; SMN2 (0.59) MALT1MEN1POLBBLMKMT2A
SCHEMBL29587040 0.91 MALT1 (0.62) MALT1MEN1POLBBLMKMT2A
SCHEMBL7557626 0.91 MALT1 (0.62) MALT1MEN1POLBBLMKMT2A
SCHEMBL31218590 0.91 MALT1 (0.62) MALT1MEN1POLBBLMKMT2A
SCHEMBL10399866 0.85 SMN1; SMN2 (0.54) MALT1MEN1POLBBLMKMT2A
SCHEMBL19749970 0.84 MEN1 (0.48) MALT1MEN1POLBBLMKMT2A
SCHEMBL10399654 0.84 SMN1; SMN2 (0.53) MALT1MEN1POLBBLMKMT2A
SCHEMBL31218592 0.83 SMN1; SMN2 (0.62) MALT1MEN1POLBBLMKMT2A
SCHEMBL6671719 0.83 MALT1 (0.54) MALT1MEN1POLBBLMKMT2A
SCHEMBL18984755 0.82 SMN1; SMN2 (0.67) MALT1MEN1POLBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475257-B1 ACETALANTHRAQUINONE DERIVATIVES USEFUL FOR CELLULAR STAINING BIOSTATUS LTD (GB) 2023-06-07 EP disclosed
EP-3475257-B1 ACETALANTHRAQUINONE DERIVATIVES USEFUL FOR CELLULAR STAINING BIOSTATUS LTD (GB) 2023-06-07 EP disclosed
US-11447638-B2 Acetalanthraquinone derivatives useful for cellular staining BIOSTATUS LIMITED (GB) 2022-09-20 US disclosed
US-11447638-B2 Acetalanthraquinone derivatives useful for cellular staining BIOSTATUS LIMITED (GB) 2022-09-20 US disclosed
US-20190249011-A1 ACETALANTHRAQUINONE DERIVATIVES USEFUL FOR CELLULAR STAINING BIOSTATUS LIMITED (GB) 2019-08-15 US disclosed
US-20190249011-A1 ACETALANTHRAQUINONE DERIVATIVES USEFUL FOR CELLULAR STAINING BIOSTATUS LIMITED (GB) 2019-08-15 US disclosed
EP-3475257-A1 ACETALANTHRAQUINONE DERIVATIVES USEFUL FOR CELLULAR STAINING Biostatus Limited (GB) 2019-05-01 EP disclosed
WO-2017220969-A1 ACETALANTHRAQUINONE DERIVATIVES USEFUL FOR CELLULAR STAINING BIOSTATUS LIMITED (GB) 2017-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11447638-B2 Acetalanthraquinone derivatives useful for cellular staining ERH, NR2E3, NR0B2 MALT1 3195/4885MEN1 3372/4885POLB 450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.