Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 7/20 | 0.57 |
| ▸ | CYBB | P04839 | 1/20 | 0.57 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.57 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20842835 | 0.89 | NOX1 (0.68) | NOX1CYBBNOX3NOX4BCHE | |
| SCHEMBL7673182 | 0.85 | NOX1 (0.62) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL30697368 | 0.85 | NOX1 (0.62) | NOX1BCHEACHEMAPTGAA | |
| Hydrochloric Acid SCHEMBL30448208 | 0.83 | NOX1 (0.60) | NOX1BCHEACHEMAPTGAA | |
| Hydrochloric Acid SCHEMBL20495637 | 0.83 | NOX1 (0.60) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL10372692 | 0.81 | NOX1 (0.84) | NOX1CYBBNOX3NOX4BCHE | |
| SCHEMBL30811565 | 0.81 | NOX1 (0.84) | NOX1CYBBNOX3NOX4BCHE | |
| SCHEMBL21196639 | 0.81 | NOX1 (0.38) | NOX1CYBBNOX3NOX4BCHE | |
| SCHEMBL19744465 | 0.79 | NOX1 (0.57) | NOX1CYBBNOX3NOX4BCHE | |
| SCHEMBL28117917 | 0.78 | NOX1 (0.76) | NOX1CYBBNOX3NOX4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475277-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | Bioimics AB (SE) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017222466-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2017-12-28 | — | — | WO | disclosed |