Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 7/20 | 0.62 |
| ▸ | BCHE | P06276 | 3/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | SNCA | P37840 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673182 | 1.00 | NOX1 (0.62) | NOX1BCHEACHESNCAMAPT | |
| Hydrochloric Acid SCHEMBL20495637 | 0.98 | NOX1 (0.60) | NOX1BCHEACHESNCAMAPT | |
| Hydrochloric Acid SCHEMBL30448208 | 0.98 | NOX1 (0.60) | NOX1BCHEACHESNCAMAPT | |
| SCHEMBL239261 | 0.90 | NOX1 (0.79) | NOX1BCHEACHESNCAMAPT | |
| SCHEMBL30769670 | 0.90 | NOX1 (0.79) | NOX1BCHEACHESNCAMAPT | |
| SCHEMBL4708136 | 0.90 | NOX1 (0.58) | NOX1BCHEACHESNCAMAPT | |
| SCHEMBL19744471 | 0.85 | NOX1 (0.57) | NOX1BCHEACHESNCAMAPT | |
| SCHEMBL1855994 | 0.84 | NOX1 (0.65) | NOX1BCHEACHESNCAMAPT | |
| SCHEMBL20495638 | 0.82 | NOX1 (0.46) | NOX1BCHEACHESNCAMAPT | |
| SCHEMBL1509784 | 0.82 | NOX1 (0.68) | NOX1BCHEACHESNCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327028-B | Phenothiazine derivative, pharmaceutical composition and application thereof in treating echinococcosis | 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) | 2024-07-23 | — | — | CN | disclosed |
| CN-117327028-A | Phenothiazine derivative, pharmaceutical composition and application thereof in treating echinococcosis | 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) | 2024-01-02 | — | — | CN | disclosed |