SCHEMBL7673182

SCHEMBL7673182

Clc1ccc2c(c1)Sc1cc(Cl)ccc1N2

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 7/20 0.62
BCHE P06276 3/20 0.62
ACHE P22303 3/20 0.62
SNCA P37840 6/20 0.50
MAPT P10636 4/20 0.46
GAA P10253 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
MAOA P21397 1/20 0.46
CNR1 P21554 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2C P28335 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30697368 1.00 NOX1 (0.62) NOX1BCHEACHESNCAMAPT
Hydrochloric Acid SCHEMBL20495637 0.98 NOX1 (0.60) NOX1BCHEACHESNCAMAPT
Hydrochloric Acid SCHEMBL30448208 0.98 NOX1 (0.60) NOX1BCHEACHESNCAMAPT
SCHEMBL239261 0.90 NOX1 (0.79) NOX1BCHEACHESNCAMAPT
SCHEMBL30769670 0.90 NOX1 (0.79) NOX1BCHEACHESNCAMAPT
SCHEMBL4708136 0.90 NOX1 (0.58) NOX1BCHEACHESNCAMAPT
SCHEMBL19744471 0.85 NOX1 (0.57) NOX1BCHEACHESNCAMAPT
SCHEMBL1855994 0.84 NOX1 (0.65) NOX1BCHEACHESNCAMAPT
SCHEMBL20495638 0.82 NOX1 (0.46) NOX1BCHEACHESNCAMAPT
SCHEMBL1509784 0.82 NOX1 (0.68) NOX1BCHEACHESNCAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11261403-B2 Stabilized compositions comprising leuco compounds MILLIKEN & COMPANY (US) 2022-03-01 US claimed
US-11136535-B2 Leuco colorants as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2021-10-05 US claimed
EP-3830232-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS The Procter & Gamble Company (US) 2021-06-09 EP claimed
CN-112513238-A Stable compositions comprising leuco compounds 美利肯公司 2021-03-16 CN claimed
WO-2020023812-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2020-01-30 WO claimed
US-20200032173-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2020-01-30 US claimed
US-20200032167-A1 STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS MILLIKEN & COMPANY 2020-01-30 US claimed
US-11916198-B2 Fast-charging lithium ion batteries with electrolytes that do not react on the anodes StoreDot Ltd. (IL) 2024-02-27 US disclosed
CN-117327028-A Phenothiazine derivative, pharmaceutical composition and application thereof in treating echinococcosis 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) 2024-01-02 CN disclosed
US-20230392018-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS MILLIKEN & COMPANY 2023-12-07 US disclosed
EP-4237498-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS Milliken & Company (US) 2023-09-06 EP disclosed
WO-2022093189-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS MILLIKEN & COMPANY (US) 2022-05-05 WO disclosed
US-11261403-B2 Stabilized compositions comprising leuco compounds MILLIKEN & COMPANY (US) 2022-03-01 US disclosed
US-20170137428-A1 AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY MERCK PATENT GMBH (DE) 2017-05-18 US disclosed
US-20170137428-A1 AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY MERCK PATENT GMBH (DE) 2017-05-18 US disclosed
EP-3164397-A1 AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY Merck Patent GmbH (DE) 2017-05-10 EP disclosed
WO-2016000827-A1 AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY MERCK PATENT GMBH (DE) 2016-01-07 WO disclosed
WO-2016000827-A1 AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY MERCK PATENT GMBH (DE) 2016-01-07 WO disclosed
US-6476021-B1 Compounds having cGMP-PDE inhibitory effect MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2002-11-05 US disclosed
EP-1048666-A1 NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170137428-A1 AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY ACHE, PARK7, CYP51A1 NOX1 3388/4885BCHE 11/4885ACHE 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.