SCHEMBL19745040

SCHEMBL19745040

C1=C2C[C]2c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.40
GPR84 Q9NQS5 1/20 0.33
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
CDC25A P30304 1/20 0.32
CDC25B P30305 1/20 0.32
MAOA P21397 1/20 0.31
DRD2 P14416 2/20 0.30
DRD4 P21917 2/20 0.30
PTAFR P25105 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29672905 0.68 PTGS2 (0.67) PTGS2GPR84CYP11B1CYP11B2MAOA
SCHEMBL7180542 0.68 PTGS2 (0.67) PTGS2GPR84CYP11B1CYP11B2MAOA
SCHEMBL7172726 0.67 PTGS2 (0.65) PTGS2GPR84CYP11B1CYP11B2MAOA
SCHEMBL29606538 0.67 PTGS2 (0.65) PTGS2GPR84CYP11B1CYP11B2MAOA
Hydrochloric Acid SCHEMBL17835934 0.65 PTGS2 (0.62) PTGS2GPR84CYP11B1CYP11B2MAOA
Hydrochloric Acid SCHEMBL29672906 0.65 PTGS2 (0.62) PTGS2GPR84CYP11B1CYP11B2MAOA
Hydrochloric Acid SCHEMBL16516153 0.64 PTGS2 (0.61) PTGS2GPR84CYP11B1CYP11B2MAOA
SCHEMBL5886591 0.64 ABCG2 (0.39) GPR84CDC25ACDC25BMAOADRD2
SCHEMBL10354666 0.64 ABCG2 (0.39) GPR84CDC25ACDC25BMAOADRD2
SCHEMBL7205941 0.63 PTGS2 (0.57) PTGS2GPR84CYP11B1CYP11B2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017223033-A1 AQUEOUS FRESHENING COMPOSITIONS AND FRESHENING PRODUCTS COMPRISING THE AQUEOUS FRESHENING COMPOSITIONS CONTAINED IN PRESSURIZED PLASTIC CONTAINERS THE PROCTER & GAMBLE COMPANY (US) 2017-12-28 WO disclosed