SCHEMBL19746062

SCHEMBL19746062

C=CC=COC(=O)CCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 3/20 0.38
LMNA P02545 3/20 0.38
KDM6B O15054 1/20 0.38
KDM5C P41229 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
ABCC4 O15439 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
BLM P54132 1/20 0.32
SLC6A3 Q01959 1/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19746063 0.91 TSHR (0.32) TSHR
SCHEMBL19746061 0.91 TSHR (0.32) TSHR
SCHEMBL25428494 0.88 ABCC4 (0.44) LMNAABCC4MAPTTSHRMEN1
SCHEMBL27691616 0.83 ALDH1A1 (0.39) LMNAABCC4MAPTTSHR
SCHEMBL28774913 0.81 LMNA (0.42) LMNAABCC4MAPTTSHR
SCHEMBL28213970 0.81 LMNA (0.42) LMNAABCC4MAPTTSHR
Hexanoate SCHEMBL28828199 0.81 AKR1B1 (0.52) LMNAMAPTTSHRBLMMEN1
SCHEMBL329073 0.78 LMNA (0.45) EGLN1LMNAKDM6BKDM5CPHF8
Succinic Acid SCHEMBL9719479 0.78 LMNA (0.45) EGLN1LMNAKDM6BKDM5CPHF8
SCHEMBL28055752 0.78 LMNA (0.45) EGLN1LMNAKDM6BKDM5CPHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899918-B2 Hydrolysis resistant vinyl ester containing latexes ARKEMA INC. (US) 2021-01-26 US disclosed
US-20190144658-A1 HYDROLYSIS RESISTANT VINYL ESTER CONTAINING LATEXES ARKEMA INC. 2019-05-16 US disclosed
EP-3472216-A1 HYDROLYSIS RESISTANT VINYL ESTER CONTAINING LATEXES Arkema Inc. (US) 2019-04-24 EP disclosed
CN-109312033-A Hydrolysis-resistant latices containing vinyl esters 阿科玛股份有限公司 2019-02-05 CN disclosed
WO-2017222979-A1 HYDROLYSIS RESISTANT VINYL ESTER CONTAINING LATEXES ARKEMA INC. (US) 2017-12-28 WO disclosed
CN-107406568-A Crystallization thermoplastic urethane composition for hot-melt adhesive 路博润先进材料公司 2017-11-28 CN disclosed