⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373166 | 0.67 | HSP90AA1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL4760945 | 0.64 | HSP90AA1 (0.47) | — | |
| SCHEMBL71024 | 0.64 | — | — | |
| Formaldehyde SCHEMBL3745731 | 0.62 | — | — | |
| SCHEMBL1829376 | 0.62 | — | — | |
| SCHEMBL437703 | 0.62 | — | — | |
| SCHEMBL7328310 | 0.62 | — | — | |
| SCHEMBL2320499 | 0.61 | — | — | |
| SCHEMBL9952074 | 0.61 | — | — | |
| SCHEMBL13911007 | 0.61 | HSP90AA1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206771-A | Covalent organic framework nano material and preparation method and application thereof | 海南大学 | 2024-06-18 | — | — | CN | claimed |
| US-20230372309-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | KYOTO UNIVERSITY (JP) | 2023-11-23 | — | — | US | claimed |
| EP-4218818-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | Kyoto University (JP) | 2023-08-02 | — | — | EP | claimed |
| CN-116234578-A | Alpha 2 adrenoreceptor antagonists | 国立大学法人京都大学 | 2023-06-06 | — | — | CN | claimed |
| CN-107635960-B | Oxime ester compound and polymerization initiator containing the same | 株式会社艾迪科 | 2022-02-01 | — | — | CN | claimed |
| CN-107864625-A | Combination product containing 2,3 substituted glyoxalidine simultaneously [1,2 c] quinazoline | 拜耳制药股份公司 | 2018-03-30 | — | — | CN | claimed |
| CN-106749268-A | Heteroaryl compound and its application in medicine | 广东东阳光药业有限公司 | 2017-05-31 | — | — | CN | claimed |
| US-8344018-B2 | Oxindolyl inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2013-01-01 | — | — | US | claimed |
| US-8134000-B2 | Imidazolyl pyrimidine inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2012-03-13 | — | — | US | claimed |
| US-8124764-B2 | Fused heterocyclyc inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2012-02-28 | — | — | US | claimed |
| EP-1367893-A1 | PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2003-12-10 | — | — | EP | claimed |
| WO-2002067684-A1 | PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-09-06 | — | — | WO | claimed |
| WO-2001060797-A1 | PHENYL-SUBSTITUTED HETEROCYCLIC ENAMINONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-23 | — | — | WO | claimed |
| EP-0571822-B1 | Diazabicycloalkene derivatives | DAIICHI SEIYAKU CO (JP) | 2001-08-16 | — | — | EP | claimed |
| US-5686392-A | Process for preparing substituted N-carbamoyl-Tetrazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-11 | — | — | US | claimed |
| CN-1136560-A | Preparing method for substituted N-amino formyl tetrazolinone | BAYER CO LTD (DE) | 1996-11-27 | — | — | CN | claimed |
| EP-0726259-A1 | Process for the preparation of substituted N-carbamoyl-tetrazolinones | BAYER AG (DE) | 1996-08-14 | — | — | EP | claimed |
| US-5418232-A | Hypotensive, increases renal blood flow | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-23 | — | — | US | claimed |
| EP-0107979-B1 | NOVEL PHENYL-SUBSTITUTED SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-12 | — | — | EP | claimed |
| EP-0107979-A1 | Novel phenyl-substituted sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-09 | — | — | EP | claimed |