Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | SNCA | P37840 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17996072 | 0.84 | SNCA (0.46) | NOX1MAPTGAAMAPK1NPC1 | |
| SCHEMBL7494277 | 0.84 | MAOA (0.41) | NOX1MAPTGAAMAPK1NPC1 | |
| SCHEMBL30499564 | 0.82 | NOX1 (0.59) | NOX1MAPTGAAMAPK1NPC1 | |
| SCHEMBL88106 | 0.82 | NOX1 (0.59) | NOX1MAPTGAAMAPK1NPC1 | |
| SCHEMBL64975 | 0.80 | SNCA (0.50) | NOX1MAPTGAAMAPK1NPC1 | |
| SCHEMBL29625245 | 0.80 | SNCA (0.50) | NOX1MAPTGAAMAPK1NPC1 | |
| SCHEMBL29600380 | 0.80 | SNCA (0.50) | NOX1MAPTGAAMAPK1NPC1 | |
| SCHEMBL237910 | 0.79 | NOX1 (0.65) | NOX1MAPTGAAMAPK1NPC1 | |
| SCHEMBL30769563 | 0.79 | NOX1 (0.65) | NOX1MAPTGAAMAPK1NPC1 | |
| Hydrochloric Acid SCHEMBL12470954 | 0.78 | SNCA (0.48) | NOX1MAPTGAAMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475277-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | Bioimics AB (SE) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017222466-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2017-12-28 | — | — | WO | disclosed |