Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.53 |
| ▸ | POLA1 | P09884 | 2/20 | 0.42 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 4/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222102 | 0.87 | PDPK1 (0.63) | PDPK1GDAPOLA1PI4KAPI4K2B | |
| SCHEMBL29605437 | 0.86 | PDPK1 (0.54) | PDPK1GDAPOLA1PI4KAPI4K2B | |
| SCHEMBL67130 | 0.86 | PDPK1 (0.54) | PDPK1GDAPOLA1PI4KAPI4K2B | |
| SCHEMBL8537687 | 0.84 | PDPK1 (0.53) | PDPK1GDAPOLA1PI4KAPI4K2B | |
| SCHEMBL1074970 | 0.84 | POLA1 (0.57) | PDPK1GDAPOLA1PI4KAPI4K2B | |
| SCHEMBL27128261 | 0.84 | PDPK1 (0.53) | PDPK1GDAPOLA1PI4KAPI4K2B | |
| SCHEMBL38912 | 0.83 | PDPK1 (0.51) | PDPK1GDAPOLA1PI4KAPI4K2B | |
| SCHEMBL29808400 | 0.83 | PDPK1 (0.51) | PDPK1GDAPOLA1PI4KAPI4K2B | |
| SCHEMBL1374742 | 0.83 | PDPK1 (0.51) | PDPK1GDAPOLA1PI4KAPI4K2B | |
| SCHEMBL28299226 | 0.83 | POLA1 (0.53) | PDPK1GDAPOLA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017222402-A1 | POLYBENZIMIDAZOLE POLYMER WITH E'UNCTIONALIZED SPACER CHAIN AND ITS METHOD OF PREPARATION FOR REMOVAL OF GENOTOXIC IMPURITIES | INSTITUTO SUPERIOR TÉCNICO (PT) | 2017-12-28 | — | — | WO | disclosed |