SCHEMBL29605437

SCHEMBL29605437

NCCCc1nc(N)c2[nH]cnc2n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.54
GDA Q9Y2T3 1/20 0.54
PI4KA P42356 2/20 0.43
PI4K2B Q8TCG2 2/20 0.43
PI4K2A Q9BTU6 2/20 0.43
PI4KB Q9UBF8 2/20 0.43
LMNA P02545 1/20 0.43
DRD3 P35462 1/20 0.43
XDH P47989 1/20 0.43
LRRK2 Q5S007 1/20 0.43
POLA1 P09884 2/20 0.43
CDK2 P24941 6/20 0.40
DPP4 P27487 1/20 0.40
CDK1 P06493 6/20 0.39
CCNB1 P14635 6/20 0.39
CCNA2 P20248 5/20 0.39
CCNA1 P78396 5/20 0.39
PIN1 Q13526 1/20 0.39
PNP P00491 1/20 0.39
KDR P35968 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67130 1.00 PDPK1 (0.54) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL1374742 0.94 PDPK1 (0.51) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL38912 0.94 PDPK1 (0.51) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL29808400 0.94 PDPK1 (0.51) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL6379588 0.90 PDPK1 (0.58) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL11222102 0.88 PDPK1 (0.63) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL19746433 0.86 PDPK1 (0.53) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL8537687 0.86 PDPK1 (0.53) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL27128261 0.86 PDPK1 (0.53) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL1074970 0.86 POLA1 (0.57) PDPK1GDAPI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095092-A Inhibitor for inhibiting inhibin Beta E gene expression and application thereof 2026-05-26 CN disclosed
CN-122095091-A DsRNA for inhibiting LPA gene expression and application thereof 2026-05-26 CN disclosed
EP-4689071-A2 MRNA THERAPEUTICS FOR OOCYTE MATURATION Eastern Virginia Medical School (US) 2026-02-11 EP disclosed
EP-4637812-A1 HEPATITIS B COMPOSITIONS GlaxoSmithKline Biologicals S.A. (BE) 2025-10-29 EP disclosed
EP-4604933-A1 METHODS AND USES ASSOCIATED WITH LIQUID COMPOSITIONS BioNTech SE (DE) 2025-08-27 EP disclosed
EP-4569112-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING AT ALTERNATIVE SPLICE SITES Remix Therapeutics Inc. (US) 2025-06-18 EP disclosed
CN-120153078-A RNA molecules encoding RSV-F and vaccines containing the same 辉瑞大药厂 2025-06-13 CN disclosed
CN-120077130-A Universal non-targeted SIRNA compositions and methods of use thereof 阿尔尼拉姆医药品有限公司 2025-05-30 CN disclosed
EP-4554617-A1 NOROVIRUS MRNA VACCINES ModernaTX, Inc. (US) 2025-05-21 EP disclosed
WO-2025096203-A1 TARGETING A CHIMERIC RNA FOR TREATING CANCER UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-05-08 WO disclosed
EP-4090664-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS Bristol-Myers Squibb Company (US) 2022-11-23 EP disclosed
CN-115244061-A Reagents and their use for modular enantioselective synthesis of C-P bonds 百时美施贵宝公司 2022-10-25 CN disclosed
CN-115176027-A Compositions and methods for light-directed biomolecular barcoding 哈佛大学校长及研究员协会 2022-10-11 CN disclosed
WO-2022212191-A1 MUCOSAL EXPRESSION OF ANTIBODY STRUCTURES AND ISOTYPES BY MRNA MODERNATX, INC. (US) 2022-10-06 WO disclosed
CN-115038790-A Synthesis of 3' -RNA oligonucleotides 阿尔尼拉姆医药品有限公司 2022-09-09 CN disclosed
CN-114945669-A Extrahepatic delivery 阿尔尼拉姆医药品有限公司 2022-08-26 CN disclosed
CN-109640962-B Polynucleotides encoding relaxin 摩登纳特斯有限公司 2022-07-19 CN disclosed
WO-2022122689-A1 RNA MANUFACTURING BioNTech SE (DE) 2022-06-16 WO disclosed
CN-114404581-A Cancer vaccine 摩登纳特斯有限公司 2022-04-29 CN disclosed
WO-2022051677-A1 COMPOSITIONS AND METHODS FOR CAPPING RNAS VERVE THERAPEUTICS, INC. (US) 2022-03-10 WO disclosed