Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.51 |
| ▸ | PI4KA | P42356 | 2/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 7/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38912 | 1.00 | PDPK1 (0.51) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL29808400 | 1.00 | PDPK1 (0.51) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL67130 | 0.94 | PDPK1 (0.54) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL29605437 | 0.94 | PDPK1 (0.54) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| Trifluoroacetic Acid SCHEMBL6509652 | 0.88 | HRH4 (0.48) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL6379588 | 0.87 | PDPK1 (0.58) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL30610405 | 0.87 | CDK1 (0.53) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL725881 | 0.87 | PDPK1 (0.50) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL11222102 | 0.85 | PDPK1 (0.63) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL28299226 | 0.85 | POLA1 (0.53) | PDPK1GDAPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universitaet Bonn Regina-Pacis-Weg 3 (DE) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | ADORA2A, ADORA1, ADORA3 | PDPK1 1768/4885GDA 508/4885PI4KA 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.