Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31601785 | 0.85 | PDE7A (0.50) | PDE7AALDH1A1LMNAMEN1HTT | |
| SCHEMBL1408443 | 0.85 | PDE7A (0.50) | PDE7AALDH1A1LMNAMEN1HTT | |
| SCHEMBL1999857 | 0.82 | PDE7A (0.54) | PDE7AALDH1A1LMNAMEN1HTT | |
| SCHEMBL8147133 | 0.79 | ALDH1A1 (0.58) | PDE7AALDH1A1HTTKMT2APOLB | |
| SCHEMBL1010657 | 0.79 | ALDH1A1 (0.53) | PDE7AALDH1A1LMNAMEN1HTT | |
| SCHEMBL30619304 | 0.79 | ALDH1A1 (0.53) | PDE7AALDH1A1LMNAMEN1HTT | |
| SCHEMBL15123102 | 0.78 | PDE7A (0.47) | PDE7AALDH1A1LMNAPOLBRORC | |
| SCHEMBL31318376 | 0.78 | HSD17B10 (0.60) | PDE7AALDH1A1KMT2APOLBRORC | |
| SCHEMBL696354 | 0.78 | ALDH1A1 (0.60) | PDE7AALDH1A1LMNAMEN1HTT | |
| SCHEMBL449256 | 0.78 | GPR35 (0.56) | PDE7AALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017223406-A1 | COMPLEXES FOR NUCLEOPHILIC, RADICAL, AND ELECTROPHILIC POLYFLUOROALKYLATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-12-28 | — | — | WO | disclosed |