Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 6/20 | 0.48 |
| ▸ | ADA | P00813 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333072 | 0.92 | ADRA1D (0.48) | CNOT7ADAADRA1D | |
| SCHEMBL19746369 | 0.90 | CNOT7 (0.49) | CNOT7HTTKMT2AALDH1A1ADORA2A | |
| SCHEMBL19746853 | 0.87 | CNOT7 (0.44) | CNOT7HTTKMT2AADRA1DALDH1A1 | |
| SCHEMBL19746852 | 0.87 | CNOT7 (0.44) | CNOT7HTTKMT2AADRA1DALDH1A1 | |
| SCHEMBL19746296 | 0.82 | SMN1; SMN2 (0.51) | CNOT7KMT2AALDH1A1 | |
| SCHEMBL31333058 | 0.81 | KDM5A (0.43) | ADAKMT2AALDH1A1MEN1 | |
| SCHEMBL19746854 | 0.81 | CNOT7 (0.47) | CNOT7HTTKMT2AALDH1A1ADORA2A | |
| SCHEMBL19468944 | 0.81 | ADORA2A (0.50) | CNOT7HTTKMT2AALDH1A1ADORA2A | |
| SCHEMBL27730799 | 0.78 | CNOT7 (0.51) | CNOT7HTTKMT2AALDH1A1ADORA2A | |
| SCHEMBL7988810 | 0.75 | ADORA2A (0.51) | CNOT7ADAHTTKMT2AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320386-A | METTL3 inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2025-01-17 | — | — | CN | disclosed |
| WO-2017222952-A1 | 3- HETEROARYL SUBSTITUTED 5-TRIFLUOROMETHYL OXADIAZOLES AS HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-12-28 | — | — | WO | disclosed |