Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADA | P00813 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747084 | 0.92 | CNOT7 (0.48) | ADRA1DCNOT7ADA | |
| SCHEMBL19746369 | 0.82 | CNOT7 (0.49) | CNOT7TSHRKDM4E | |
| SCHEMBL19746853 | 0.79 | CNOT7 (0.44) | ADRA1DCNOT7HTR1AHTR7 | |
| SCHEMBL19746852 | 0.79 | CNOT7 (0.44) | ADRA1DCNOT7HTR1AHTR7 | |
| SCHEMBL7992360 | 0.77 | ADRA1D (0.46) | ADRA1DCNOT7TSHRLMNAKDM4E | |
| SCHEMBL31333058 | 0.76 | KDM5A (0.43) | ADA | |
| SCHEMBL19746296 | 0.74 | SMN1; SMN2 (0.51) | CNOT7TSHRLMNAKDM4EPOLB | |
| SCHEMBL19746854 | 0.74 | CNOT7 (0.47) | CNOT7KDM4EHTR1AHTR7 | |
| SCHEMBL29830638 | 0.73 | ADRA1D (0.48) | ADRA1DCNOT7TSHRLMNAKDM4E | |
| SCHEMBL19468944 | 0.73 | ADORA2A (0.50) | CNOT7HTR1AHTR7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320386-A | METTL3 inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2025-01-17 | — | — | CN | disclosed |