SCHEMBL1719765

SCHEMBL1719765

CC(=O)c1cccc2c1Nc1ccccc1S2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 8/20 0.55
GAA P10253 7/20 0.55
MAPT P10636 6/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
ALOX15 P16050 2/20 0.55
SNCA P37840 2/20 0.55
CYBB P04839 1/20 0.55
APP P05067 1/20 0.55
NOX3 Q9HBY0 1/20 0.55
NOX4 Q9NPH5 1/20 0.55
TDP1 Q9NUW8 2/20 0.50
POLB P06746 2/20 0.50
CYP1A2 P05177 1/20 0.50
BCHE P06276 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
ALOX12 P18054 1/20 0.50
MAOA P21397 1/20 0.50
CNR1 P21554 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31657639 1.00 NOX1 (0.55) NOX1GAAMAPTMEN1KMT2A
Maleic Acid SCHEMBL27887887 0.92 GAA (0.48) NOX1GAAMAPTMEN1KMT2A
SCHEMBL293434 0.89 ALOX5 (0.54) NOX1GAAMAPTMEN1KMT2A
Benzene SCHEMBL28125613 0.89 ALOX5 (0.54) NOX1GAAMAPTMEN1KMT2A
SCHEMBL27607313 0.88 NOX1 (0.55) NOX1GAAMAPTMEN1KMT2A
SCHEMBL5362784 0.85 NOX1 (0.52) NOX1GAAMAPTMEN1KMT2A
SCHEMBL1509833 0.84 NOX1 (0.50) NOX1GAAMAPTMEN1KMT2A
SCHEMBL7162110 0.84 NOX1 (0.50) NOX1GAAMAPTMEN1KMT2A
SCHEMBL9855906 0.83 NOX1 (0.46) NOX1GAAMAPTMEN1KMT2A
SCHEMBL547518 0.83 NOX1 (0.48) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114084877-B Method for obtaining ultrapure ferric phosphate from waste lithium iron phosphate pole piece material and obtained ultrapure ferric phosphate 长沙理工大学 2024-01-16 CN claimed
CN-114084877-A Method for obtaining ultrapure iron phosphate from waste lithium iron phosphate electrode plate material and obtained ultrapure iron phosphate 长沙理工大学 2022-02-25 CN claimed
CN-108484527-B 10H-phenothiazine iron death inhibitor and preparation method and application thereof 成都恒昊创新科技有限公司 2022-01-14 CN claimed
CN-108484527-A 10H-phenothiazine iron death inhibitor and preparation method and application thereof 四川大学 2018-09-04 CN claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
EP-0496816-A4 POLYMERIZATION REACTOR SCALE PREVENTION 1992-10-28 EP claimed
EP-0496816-A1 POLYMERIZATION REACTOR SCALE PREVENTION OCCIDENTAL CHEMICAL CORPORATION (US) 1992-08-05 EP claimed
WO-1991006576-A1 POLYMERIZATION REACTOR SCALE PREVENTION OCCIDENTAL CHEMICAL CORPORATION (US) 1991-05-16 WO claimed
CN-1051044-A Polymerization reactor fouling prevents OCCIDENTAL CHEM CO (US) 1991-05-01 CN claimed
US-4175195-A REACTING A (HETERO-)AROMATIC KETONE, AMMONIA, AND AN UNSATURATED KETONE OR ALDEHYDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-11-20 US claimed
CN-114084877-B Method for obtaining ultrapure ferric phosphate from waste lithium iron phosphate pole piece material and obtained ultrapure ferric phosphate 长沙理工大学 2024-01-16 CN disclosed
CN-116425701-A Novel efficient synthesis method of acetyl perphenazine dimaleate 广州佳途科技股份有限公司 2023-07-14 CN disclosed
CN-114084877-A Method for obtaining ultrapure iron phosphate from waste lithium iron phosphate electrode plate material and obtained ultrapure iron phosphate 长沙理工大学 2022-02-25 CN disclosed
WO-2016180784-A1 IMPROVED TREATMENTS USING OLIGONUCLEOTIDES PROQR THERAPEUTICS II B.V. (NL) 2016-11-17 WO disclosed
EP-0496816-A4 POLYMERIZATION REACTOR SCALE PREVENTION 1992-10-28 EP disclosed
EP-0496816-A1 POLYMERIZATION REACTOR SCALE PREVENTION OCCIDENTAL CHEMICAL CORPORATION (US) 1992-08-05 EP disclosed
WO-1991006576-A1 POLYMERIZATION REACTOR SCALE PREVENTION OCCIDENTAL CHEMICAL CORPORATION (US) 1991-05-16 WO disclosed
US-4175195-A REACTING A (HETERO-)AROMATIC KETONE, AMMONIA, AND AN UNSATURATED KETONE OR ALDEHYDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-11-20 US disclosed
US-4171444-A REACTING A (HETERO-)AROMATIC KETONE, AMMONIA, AND AN ALIPHATIC ALDEHYDE, DEHYDRATING-DEHYDROGENATION CATALYSTS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA NOX1 1526/4885GAA 130/4885MAPT 1630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.