Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21289128 | 0.81 | SLC18A3 (0.44) | OPRL1OPRM1OPRK1SLC18A3ALDH1A1 | |
| SCHEMBL18088246 | 0.76 | OPRL1 (0.35) | OPRL1OPRM1OPRK1ALDH1A1TSHR | |
| SCHEMBL1869057 | 0.76 | HTR2A (0.55) | OPRL1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL13276577 | 0.76 | HTR2A (0.55) | OPRL1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL17169559 | 0.75 | TSHR (0.34) | OPRL1OPRM1OPRK1ALDH1A1TSHR | |
| SCHEMBL17169599 | 0.73 | ALDH1A1 (0.40) | OPRL1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL30530617 | 0.73 | MEN1 (0.40) | OPRL1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL17169565 | 0.73 | PDE9A (0.34) | OPRL1OPRM1OPRK1SLC18A3ALDH1A1 | |
| SCHEMBL17169586 | 0.72 | C5AR1 (0.34) | OPRL1OPRM1OPRK1ALDH1A1TSHR | |
| SCHEMBL24226530 | 0.71 | TSHR (0.39) | OPRL1OPRM1OPRK1SLC18A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9853229-B2 | Organic electroluminescent materials and devices | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-12-26 | — | — | US | disclosed |