Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 3/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13276577 | 1.00 | HTR2A (0.55) | HTR2AHTR2CHTR2BNOTUMALDH1A1 | |
| SCHEMBL24315481 | 0.91 | HTR2A (0.60) | HTR2AHTR2CHTR2BNOTUMALDH1A1 | |
| SCHEMBL17339956 | 0.85 | HTR2A (0.54) | HTR2AHTR2CHTR2BNOTUMALDH1A1 | |
| SCHEMBL23784184 | 0.77 | HTR2A (0.40) | HTR2AHTR2CHTR2BNOTUMALDH1A1 | |
| SCHEMBL19749032 | 0.76 | OPRL1 (0.45) | ALDH1A1LMNAHTTOPRM1OPRK1 | |
| Fluorobenzene SCHEMBL27513534 | 0.73 | ALDH1A1 (0.47) | HTR2AHTR2CHTR2BALDH1A1CHRM2 | |
| SCHEMBL14169897 | 0.73 | OPRM1 (0.40) | ALDH1A1LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL14170247 | 0.71 | XIAP (0.38) | HTR2AHTR2CHTR2BALDH1A1BRD4 | |
| SCHEMBL6942296 | 0.71 | SRD5A1 (0.48) | HTR2AHTR2CHTR2BNOTUMCHRM2 | |
| SCHEMBL14705297 | 0.70 | NOTUM (0.55) | HTR2AHTR2CHTR2BNOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | disclosed |
| EP-2493853-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051394-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263848-A1 | Organic Compounds | OR10J3, CBR3, C9 | HTR2A 2254/4885HTR2C 1774/4885HTR2B 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.