Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | IDE | P14735 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177550 | 0.96 | KDM4E (0.66) | KDM4EALDH1A1RXFP1POLBMAPT | |
| SCHEMBL5708457 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1RXFP1POLBMAPT | |
| Water SCHEMBL1048309 | 0.84 | KDM4E (0.57) | KDM4EALDH1A1RXFP1POLBMAPT | |
| SCHEMBL13645489 | 0.83 | KDM4E (0.64) | KDM4EPOLBMAPTRECQLHTT | |
| SCHEMBL1002934 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1RXFP1POLBMAPT | |
| SCHEMBL13686278 | 0.81 | KDM4E (0.62) | KDM4EPOLBRECQL | |
| SCHEMBL12201138 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1POLBMAPTKMT2A | |
| SCHEMBL11579424 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1POLBMAPTKMT2A | |
| SCHEMBL19485776 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1POLBMAPTKMT2A | |
| SCHEMBL12849714 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10935498-B1 | Fluorescent probe for detecting nitroreductase and preparation method and use thereof in enzymatic reaction | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2021-03-02 | — | — | US | disclosed |
| US-9850382-B1 | Unsymmetrical cyanine dyes and their application | Ying, Laiqiang (US) | 2017-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10935498-B1 | Fluorescent probe for detecting nitroreductase and preparation method and use thereof in enzymatic reaction | POR, CBR3, NQO1 | KDM4E 3253/4885ALDH1A1 138/4885RXFP1 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.